Topic: Analysis of neuroinflammatory cell mechanisms associated with neurodegenerative
process in Parkinson's disease: a systematic review
Proposed by: Mirian David, Renaly Rodrigues, Carlúcia Franco, Clarissa Bezerra
Review question: What are the neuroinflammatory cellular mechanisms associated with the neurodegenerative process in Parkinson's Disease?
The main key difference is that Mirian et.al. are investigating how the immune response of astrocytes and microglia are showing up in post mortem brain slices, whilst we are proposing to look at changes and mutations in protein structures and mitochondria in neural cells using proteomics and Seahorse oxidative respiration analysis.
